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W Keil, M Kaschube, M Schnabel, Z F Kisvarday, S Löwel, D M Coppola, L E White, and F Wolf (2012)

Response to Comment on "Universality in the evolution of orientation columns in the visual cortex"

Science 336(6080):413.  (export entry)


Meng et al. conjecture that pinwheel density scales with body and brain size. Our data, spanning a 40-fold range of body sizes in Laurasiatheria and Euarchonta, do not support this conclusion. The noncolumnar layout in Glires also appears size-insensitive. Thus, body and brain size may be understood as a constraint on the evolution of visual cortical circuitry, but not as a determining factor.