Home Publications Phase contrast tomography of the mouse cochlea at microfocus x-ray sources
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M. Bartels, V. H. Hernandez, M. Krenkel, T. Moser, and T. Salditt (2013)

Phase contrast tomography of the mouse cochlea at microfocus x-ray sources

Applied Physics Letters 103(8):083703-1-5.  (export entry)


We present phase contrast x-ray tomography of functional soft tissue within the bony cochlear capsule of mice, carried out at laboratory microfocus sources with well-matched source, detector, geometry, and reconstruction algorithms at spatial resolutions down to 2 lm. Contrast, data quality and resolution enable the visualization of thin membranes and nerve fibers as well as automated segmentation of surrounding bone. By complementing synchrotron radiation imaging techniques, a broad range of biomedical applications becomes possible as demonstrated for optogenetic cochlear implant research.